PETHIDINE (pharmacokinetic profile)

Structure/Class
  1. Phenylpeperidine
Pharmacodynamics
  1. As above
Absorption/administration
Distribution
Metabolism
  1. Hepatic
    • Importantly, pethidine has an active metabolite known as norpethidine that accumulates in renal failure. This metabolite causes seizures.
Excretion
  1. Renal
Special notes